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VDRL Test for Cerebrospinal Fluid (CSF)

What is VDRL test for CSF?

The Venereal Disease Research Laboratory (VDRL) test is a blood test for syphilis that can also be performed on cerebrospinal fluid (CSF) when neurosyphilis (syphilis infection involving the central nervous system) is suspected. The VDRL test works by detecting the presence of antibodies, proteins produced by the immune system in response to the presence of the bacterium Treponema pallidum, the causative agent of syphilis.

  • Test NameUnderstanding the VDRL Test - Cerebrospinal Fluid (CSF)
  • Sample TypeCSF
  • Preparations RequiredNo specific preparations are necessary for this test.
  • Report Time4 hours

Purpose of VDLR Test

Syphilis is a sexually transmitted infection that can cause serious health issues if not promptly treated. The disease can affect multiple organs, including the brain and the spinal cord, resulting in neurosyphilis, which can cause severe neurological problems. The VDRL test performed on CSF is an important tool for diagnosing this condition, as it allows for the detection of antibodies directly in the central nervous system, where the bacteria may be located.

VDLR Test procedure

A lumbar puncture (or spinal tap) is needed to collect the CSF sample. This procedure involves inserting a needle into the lower part of the spine to withdraw a small amount of fluid for testing. The VDRL test has high specificity; however, its sensitivity is not perfect, meaning that it can sometimes yield false-negative results. Therefore, a negative result does not rule out neurosyphilis, and further tests may be required based on clinical judgment.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports

Frequently Asked Questions

The VDRL test for cerebrospinal fluid (CSF) detects the presence of syphilis in the nervous system, specifically neurosyphilis. This test detects antibodies against the syphilis bacterium, which is crucial for diagnosing and treating the infection.

The test is performed on CSF to detect neurosyphilis, a condition where syphilis infects the central nervous system.

Individuals who are at risk for to syphilis, including those who have multiple sexual partners, individuals who are HIV-positive, pregnant women, and those experiencing symptoms such as genital sores or rash, should contemplate undergoing a VDRL test.

Symptoms of syphilis detected by the VDRL test include painless sores, rash, fever, swollen lymph nodes, and fatigue. If left untreated, syphilis can cause neurological and cardiovascular complications in later stages.

VDRL may stay positive for life after syphilis infection, even if treated successfully. It indicates past or current exposure to the syphilis bacterium, but does not necessarily mean active infection.

Yes, syphilis can be cured with antibiotics, typically penicillin. Early detection and treatment are crucial to prevent complications. Regular testing and safe sexual practices help prevent transmission.

If a syphilis test is positive, it indicates exposure to the syphilis bacterium. Further tests are needed to confirm the stage of infection and determine appropriate treatment. Early treatment with antibiotics can cure syphilis and prevent complications.

A negative VDRL test usually indicates that there are no syphilis antibodies found in the blood during the test. However, it may not completely rule out syphilis, especially in the early stages. Additional testing might be needed to confirm.

While the principle of the tests is the same, the VDRL CSF test specifically checks for syphilis in the brain or spinal cord, while the VDRL blood test checks for syphilis in the bloodstream.

Additional tests to diagnose neurosyphilis involve analyzing cerebrospinal fluid (CSF) for increased levels of white blood cells and protein, as well as conducting CSF treponemal tests such as FTA-ABS or TPPA. Brain imaging may also be performed to evaluate any potential neurological harm.

Yes, a pregnant woman with syphilis can pass the infection to her baby during pregnancy or childbirth, leading to congenital syphilis. This can result in serious health issues or even death for the baby if not treated promptly.

No, syphilis cannot be transmitted through contact with toilet seats. It can only be transmitted through direct contact with syphilitic sores or mucous membranes during sexual activity.

The price of VDRL test in Hyderabad is just Rs.350/-. Sprint Diagnostics provides pathology lab tests at an affordable price. Schedule your diagnostic tests now!

VDRL (RPR), CSF
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