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Sickle Cell DNA PCR

The Sickle Cell DNA PCR (Polymerase Chain Reaction) test is a molecular diagnostic test used to detect sickle cell disease or sickle cell trait. Sickle cell disease is a genetic disorder that affects the hemoglobin in red blood cells, causing them to become rigid and shaped like a "C" or sickle. This can lead to various health problems including painful episodes, anemia, and increased susceptibility to infections.


  • Test NameSickle Cell DNA PCR
  • Sample TypeBlood
  • Preparations RequiredNo special preparation is needed for this test.
  • Report Time5 Days

The PCR test works by amplifying a small sample of DNA to identify specific genetic sequences associated with the sickle cell mutation. It's a highly sensitive and specific test, making it an excellent tool for early diagnosis and carrier detection.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

This test is performed to detect the presence of the sickle cell gene mutation, either for the diagnosis of sickle cell disease in symptomatic individuals or for carrier screening in at-risk populations.

No, fasting is not required for this test.

The test identifies specific genetic sequences in your DNA associated with the sickle cell mutation.

This test is typically only performed once for diagnostic or carrier detection purposes. However, your doctor might recommend more frequent testing based on your specific circumstances.

A negative result indicates the absence of the sickle cell mutation. A positive result indicates the presence of the mutation and may signify sickle cell disease or sickle cell trait, depending on other clinical and laboratory findings.

No specific precautions are required for this test. However, inform your doctor about all medications, vitamins, or supplements you are taking.

There are no modifiable factors that affect the results of this test, as it examines a genetic characteristic.

Non-modifiable factors include your genetic makeup, as the test is designed to detect a genetic mutation.

You should consult your doctor if your test results are abnormal. They can help interpret the results and guide you on the next steps.

The test involves a routine blood draw, which carries minimal risks, such as slight pain, bruising, or infection at the puncture site.

No. Since this test detects a genetic mutation, it is not affected by other medical conditions.

No. This test examines your genetic makeup, and medications do not influence the results.

A positive result indicates the presence of the sickle cell mutation. This could mean you have sickle cell disease or the sickle cell trait, depending on other clinical findings.

Since the test results reflect your genetic makeup, there is nothing you can do to change them. However, if you are diagnosed with sickle cell disease, appropriate management can help control symptoms and prevent complications.

Treatments for sickle cell disease may include pain relief medication, blood transfusions, and other therapies to manage symptoms. In some cases, a bone marrow transplant may be considered.

Sickle cell disease predominantly affects people of African, Middle Eastern, Mediterranean, and Indian descent. Therefore, individuals from these ethnic backgrounds are more likely to test positive.

No specific preparation is required for this test.

A consistently positive result indicates the presence of the sickle cell mutation. This is a lifelong condition as it is related to your genetic makeup.

The Sickle Cell DNA PCR test is highly accurate in detecting the sickle cell mutation when performed in a certified lab.

Your doctor may order additional tests, such as complete blood count (CBC), hemoglobin electrophoresis, or imaging tests, to further assess your condition.

While a positive Sickle Cell DNA PCR test may be worrying, it's crucial to remember that many individuals with sickle cell trait live healthy lives, and those with sickle cell disease can manage their symptoms with appropriate care. Always consult with your doctor to understand your test results and create an appropriate management plan.

Sickle Cell DNA PCR
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