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Rheumatoid Factor (RA) - Quantitative - Synovial Fluid

Rheumatoid Factor (RF) is a type of protein produced by your immune system that can attack healthy tissues in your body. This protein is often found in higher than normal levels in people with autoimmune diseases, such as rheumatoid arthritis. When rheumatoid factor is present in the synovial fluid (the lubricating fluid found in the joints), it can indicate joint inflammation caused by an underlying autoimmune condition.


  • Test NameRheumatoid Factor (RA) - Quantitative - Synovial Fluid
  • Sample TypeSynovial Fluid
  • Preparations RequiredThere are no specific instructions for the preparation of this test. However, please inform your healthcare provider of any medications or supplements you may be taking as these can influence the test results.
  • Report Time4 hours

In the case of rheumatoid arthritis, the immune system mistakenly targets the synovial membranes lining the joints, causing inflammation, swelling, and pain. Measuring the levels of RF in the synovial fluid can be an essential diagnostic tool to help doctors diagnose and monitor the progression of rheumatoid arthritis and other related conditions.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

The test is used to detect and measure the level of rheumatoid factor in the synovial fluid. This can help in diagnosing conditions like rheumatoid arthritis and can also be used to monitor the progression of the disease and the effectiveness of treatment.

The sample for this test is collected through a procedure called arthrocentesis, where a needle is used to draw synovial fluid from a joint. This procedure is usually done under local anesthesia.

While generally safe, any procedure involving a needle carries some risks, including infection, bleeding, and discomfort at the site of puncture.

The turnaround time for the test is usually 2-3 days, but it can vary depending on the laboratory.

A high level of rheumatoid factor in the synovial fluid may indicate an autoimmune disorder such as rheumatoid arthritis. However, the RF test is not definitive on its own and is usually used in conjunction with other tests and clinical symptoms to make a diagnosis.

The level of rheumatoid factor in your synovial fluid is determined by the underlying condition causing it. Following the treatment plan set by your doctor can help control these levels.

The normal range can vary depending on the lab and method used for testing. Your healthcare provider will discuss what your specific results mean.

There are no specific preparations needed for this test. However, be sure to inform your healthcare provider of any medications or supplements you're taking.

Yes, this test can be used to monitor disease progression and the effectiveness of treatment for conditions like rheumatoid arthritis.

Synovial fluid is a thick, lubricating fluid that fills the small amount of space in the capsule surrounding your joints. It nourishes the cartilage and keeps the joint moving smoothly.

Yes, other conditions like systemic lupus erythematosus, Sjogren's syndrome, and certain infections can also cause increased RF levels.

Yes, your doctor may also order tests like C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), and antinuclear antibody (ANA) to get a better understanding of your condition.

Not always. Some people with rheumatoid arthritis may have normal RF levels. This test is just one piece of the puzzle and must be interpreted along with other tests and clinical symptoms.

The frequency of the test depends on your symptoms, the severity of the disease, and the treatment plan outlined by your doctor.

No, this test does not involve any exposure to radiation.

While both tests measure levels of Rheumatoid Factor, they are not the same. The synovial fluid test specifically checks for RF levels in the joint fluid, which can give more direct information about joint inflammation.

Yes, some medications like oral contraceptives, immunosuppressants, and some antibiotics can affect the result of this test. Always inform your healthcare provider about any medication you are currently taking.

Low levels of Rheumatoid Factor are generally considered normal. However, if you have symptoms of joint inflammation or other symptoms of an autoimmune disorder, your healthcare provider may order additional tests to help determine the cause.

The frequency of this test for someone with rheumatoid arthritis depends on several factors, including the severity of your symptoms , your response to treatment, and your healthcare provider's evaluation.

No, rheumatoid arthritis cannot be diagnosed based on a single test. Your healthcare provider will use a combination of tests, physical examination, and your medical history to diagnose this condition.

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