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PNH Flowcytometry - FLAER

Paroxysmal Nocturnal Hemoglobinuria (PNH) is a rare, acquired, life-threatening disease of the blood characterized by hemolytic anemia, thrombosis, and impaired bone marrow function. PNH is caused by the acquisition of a certain mutation in a stem cell, leading to a deficiency of proteins that normally protect red blood cells from the complement system, a part of the body's immune response.


  • Test NamePNH (Paroxysmal Nocturnal Hemoglobinuria) Flowcytometry - FLAER (CD14, CD15, CD33, CD45, CD24, FLAER)
  • Sample TypeBlood
  • Preparations RequiredNo specific preparations, dietary restrictions, or water consumption limits are needed before this test.
  • Report Time2 days

The PNH Flowcytometry - FLAER test is an advanced diagnostic tool used to confirm the diagnosis of PNH. The method involves labeling cells with fluorescent-tagged antibodies against specific cell surface proteins (CD14, CD15, CD33, CD45, CD24, FLAER) and analyzing them using a flow cytometer. This allows for the detection of cells deficient in these proteins, a hallmark of PNH.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

The test is crucial as it provides a definitive diagnosis of PNH. Early detection and diagnosis are vital for initiating appropriate treatment and managing the disease's complications.

No, fasting is not required for this test.

There are no specific preparations needed for this test. However, it's always advisable for patients to inform their healthcare provider about any medications or supplements they are taking as some of these might interfere with the test results.

This test should be performed when a patient exhibits symptoms suggestive of PNH, like dark colored urine, especially in the morning, fatigue, shortness of breath, rapid heart rate, and a propensity for developing blood clots.

This test detects the deficiency or absence of specific proteins on the surface of blood cells, thereby aiding in diagnosing PNH.

The frequency of this test depends on the patient's clinical condition and the treating physician's discretion. It is generally done for diagnostic purposes or to monitor the disease's progression.

In a healthy individual, these specific proteins should be present on the surface of blood cells. Their deficiency or absence indicates PNH.

The test involves a routine blood draw, which is generally safe. However, some people might experience minor bruising or discomfort at the site of the needle insertion.

Modifiable factors include the use of certain medications that may affect the immune system. Non-modifiable factors include genetic predisposition.

In case of abnormal results, the patient should consult a Hematologist or an Oncologist.

Yes, certain medications, particularly those that affect the immune system, can influence the test results.

Treatment for PNH focuses on easing symptoms and preventing complications. It may include medications to reduce the breakdown of red blood cells, anticoagulants to prevent clot formation, and in severe cases, stem cell transplantation.

Understanding the PNH Flowcytometry - FLAER test, its significance, and implications for diagnosis and treatment is vital for patients suspected of having PNH or confirmed cases. By allowing the detection of specific protein deficiencies on blood cells, this test plays a critical role in diagnosing and monitoring PNH. As with all diagnostic procedures, it's crucial for patients to have a clear discussion with their healthcare provider about the results and what they mean for their specific health situation. Early detection and appropriate treatment can greatly improve the prognosis for patients with PNH.

PNH (Paroxysmal Nocturnal Hemoglobinuria) Flowcytometry - FLAER (CD14, CD15, CD33, CD45, CD24, FLAER)
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Locations Near You in Hyderabad
  • 4KM from Madhapur
  • 3KM from Banjara Hills
  • 1.9KM from Yusufguda
  • 3KM from Madhura Nagar
  • 5KM from Shaikpet