Myeloperoxidase (MPO) Stain

A sample of your blood, bone marrow, or other tissues is collected and sent to a lab. The sample is stained with a special dye that reacts with myeloperoxidase, causing cells containing the enzyme to change color. These stained cells are then examined under a microscope.

If a blood sample is used, you might feel a quick prick or stinging sensation when the needle is inserted into your vein. If a bone marrow sample is used, you'll be given a local anesthetic to numb the area, but you might feel some pressure or discomfort during the procedure.

The risks associated with the MPO Stain test are minimal and mostly related to the sample collection process. For a blood sample, there's a slight risk of bruising, infection, or fainting. For a bone marrow sample, risks include bleeding and infection at the site of the biopsy.

A positive result indicates the presence of MPO in the cells, which can be a sign of AML or another myeloperoxidase-related condition. A negative result could suggest a different type of leukemia or condition. Your healthcare provider will interpret your results in the context of your symptoms and other diagnostic tests.

The turnaround time can vary depending on the lab but typically ranges from 3 to 5 days.

Yes, there are no dietary restrictions before this test.

Yes, continue taking all prescribed medications unless your healthcare provider tells you otherwise.

After the test, you can resume your normal activities. Your healthcare provider will contact you to discuss the results and any next steps.

The frequency of testing depends on your condition. If you're being monitored for AML or another related disease, your healthcare provider will recommend a testing schedule based on your specific needs.

No, the MPO Stain test requires a sample to be taken and processed in a laboratory.

Yes, the MPO Stain test can be used to monitor response to treatment in people with AML or other related conditions.

Your healthcare provider may recommend additional tests to confirm a diagnosis or evaluate your disease, such as a complete blood count (CBC), cytogenetic analysis, or molecular tests.

Yes, certain conditions, such as infections or inflammation, can increase MPO levels and could potentially affect the test results.

The MPO Stain test is generally accurate and reliable, but no test is 100% accurate. False negatives and positives can occur. Your healthcare provider will interpret your test results in conjunction with your symptoms and other diagnostic tests.

No, while a biopsy involves removing a small piece of tissue for examination under a microscope, an MPO Stain test is a type of laboratory analysis performed on that sample. They're different parts of the diagnostic process.

No specific preparation is required for the MPO Stain test. However, if the sample required is a bone marrow biopsy, you may need to prepare for that procedure according to your healthcare provider's instructions.

Yes, this test can be performed on individuals of any age, including children, if required for diagnosis or monitoring of disease.

No, the MPO Stain test isn't typically part of a routine check-up. It is performed when there is a medical reason to suspect a disease that can be identified by the presence of myeloperoxidase in cells.

There are no side effects of the test itself. However, the sample collection process can cause temporary discomfort, and in rare cases, may lead to minor complications like infection or bleeding.

Taking certain medications or having an active infection could potentially affect the results. It's essential to inform your healthcare provider about all medications you're taking and any other health conditions you have.