The Lyme disease (Borrelia burgdorferi) DNA Qualitative PCR test is a highly sensitive and specific method used to detect the presence of Borrelia burgdorferi DNA in a patient's sample. Borrelia burgdorferi is a bacterium transmitted to humans through the bite of infected black-legged ticks, and it's the primary cause of Lyme disease. This test can provide important information to help diagnose Lyme disease, especially in early stages when antibody tests may still be negative.
PCR stands for Polymerase Chain Reaction, a technology that amplifies targeted DNA sequences, making it easier to detect the presence of specific pathogens. A positive PCR result for Borrelia burgdorferi indicates an active infection, helping guide treatment decisions. As it targets the DNA of the bacterium, this test is considered more accurate and faster than conventional culture methods.
Lyme disease is a bacterial infection primarily transmitted by ticks found in wooded and grassy areas. It's caused by the bacterium Borrelia burgdorferi. Common symptoms include fever, headache, fatigue, and a characteristic skin rash.
This test is performed when Lyme disease is suspected based on exposure to ticks or symptoms. It is particularly helpful in the early stages of the disease when antibody tests may not yet be positive.
The sample type can vary depending on the patient's symptoms and the stage of the disease. It can include blood, cerebrospinal fluid, skin biopsy, or synovial fluid.
The method of sample collection depends on the type of sample being taken. Blood is drawn from a vein in your arm, cerebrospinal fluid is collected through a lumbar puncture, and a skin biopsy involves removing a small piece of skin tissue.
A positive result indicates that Borrelia burgdorferi DNA is present in the sample and that the individual tested has an active Lyme disease infection.
The turnaround time for results can vary depending on the lab, but typically, results are available within a few days.
The risks associated with this test are minimal and depend on the type of sample collected. For a blood draw, risks include slight pain, light-headedness, or bruising at the site of needle insertion.
If your test results are negative, but you're still experiencing symptoms, your healthcare provider may order additional tests to rule out other causes of your symptoms.
Yes, this test can be performed on individuals of all ages, including children.
No, this test identifies the presence of the bacterial DNA in your body, indicating an active infection. It cannot differentiate between a current and past infection.
The PCR test for Lyme disease is highly sensitive and specific, making it a reliable method for detecting the Borrelia burgdorferi bacterium.
Prevention strategies include avoiding areas where ticks live, using insect repellent, and wearing protective clothing when in wooded or grassy areas. It's also important to check your body for ticks after being in these areas.
Yes, Lyme disease can be effectively treated with antibiotics, especially when detected early.
Not necessarily. In the early stages of Lyme disease, the test may not detect the bacterium. If Lyme disease is strongly suspected, your healthcare provider may recommend a repeat test or different testing methods.
Yes, even after successful treatment, you can get infected again if you're bitten by a tick carrying the bacterium. Please note: This information is intended to provide general knowledge and is not a substitute for professional medical advice or treatment. Always consult with your healthcare provider for personalized medical advice.