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LDH (Lactate Dehydrogenase) - CSF

Lactate dehydrogenase (LDH) is an enzyme found in various tissues of the body, including the brain. It plays a vital role in the metabolism of sugar. When cells are damaged or destroyed, LDH is released into the fluid that surrounds them. In this test, the LDH levels in the cerebrospinal fluid (CSF), which is the fluid surrounding the brain and spinal cord, are measured. Elevated LDH levels in CSF may indicate various conditions including infections, diseases, or injury affecting the brain or spinal cord.


  • Test NameLDH (Lactate Dehydrogenase) - CSF
  • Sample TypeCerebrospinal Fluid (CSF)
  • Preparations RequiredNo special preparation is required for this test.
  • Report Time4 hours

The CSF is a clear fluid that cushions the brain and spinal cord while also delivering nutrients and removing waste products. Analyzing the components of CSF, including LDH, can be essential for diagnosing and monitoring diseases affecting the central nervous system.

Home Sample Collection Process

1
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2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
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Frequently Asked Questions

Lactate dehydrogenase (LDH) is an enzyme involved in the conversion of lactate to pyruvate, a critical step in producing energy for cells. Measuring LDH levels in CSF can help diagnose or monitor diseases affecting the brain and spinal cord.

The test is performed on a sample of CSF obtained through a lumbar puncture, where a needle is inserted into the lower part of the spine to collect fluid. This procedure is performed by a healthcare professional.

High levels of LDH in CSF can indicate inflammation, infection, injury, or tumors affecting the brain or spinal cord.

The primary risks are associated with the lumbar puncture procedure. These risks include headache, infection, or bleeding at the puncture site. The procedure should be performed by an experienced healthcare professional.

There are no special preparations needed for the LDH test itself. However, your doctor will provide instructions regarding preparation for the lumbar puncture procedure.

Yes, some medications may affect LDH levels in the CSF. It’s important to inform your doctor of any medications you are taking.

Your doctor might order this test if you have symptoms or signs that suggest an infection, inflammation, or other disorders affecting the central nervous system.

The normal range for LDH in CSF varies but is generally lower than that in blood. The specific range can differ between labs, so it is important to discuss your results with your doctor.

The frequency of this test depends on the medical condition being investigated and your doctor’s recommendations.

Yes, other tests such as glucose, protein, and cell count are often performed on CSF to provide more information about the health of the central nervous system.

Infection, inflammation, injury, or tumors affecting the brain or spinal cord can cause elevated LDH levels in CSF.

LDH levels in CSF reflect underlying conditions. Managing or treating the underlying condition, as advised by a doctor, can affect LDH levels.

Yes, LDH levels in CSF are often used along with other tests to help diagnose meningitis.

LDH levels can sometimes help in differentiating between bacterial and viral infections of the central nervous system, but other tests are usually required for a definitive diagnosis.

You should consult a neurologist if you have abnormal LDH levels in CSF.

Testing LDH levels in cerebrospinal fluid is a valuable tool in assessing the health of the central nervous system. It can provide crucial information about infections, inflammations, and other conditions affecting the brain and spinal cord. As always, it is important to discuss your test results with your doctor to understand what they mean in the context of your health.

LDH (Lactate Dehyderogenase) - CSF
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