HE4 (Human Epididymis Protein-4) Test

The HE4 test is a simple blood test. A healthcare professional will take a blood sample from a vein in your arm, which is then sent to a laboratory for analysis.

Elevated levels of HE4 in the blood can indicate the presence of ovarian cancer or suggest that the cancer is progressing. However, HE4 levels can also be elevated due to other conditions. It is important to interpret the results in the context of other diagnostic tests and clinical evaluation.

The risks associated with the HE4 test are minimal and are common to most blood tests. These include pain or bruising at the site where the blood was drawn.

The frequency of the HE4 test should be determined by your doctor based on your specific condition and medical history.

Yes, HE4 levels can also be elevated in conditions such as endometriosis, ovarian cysts, and certain lung cancers.

HE4 is not typically used for early detection of ovarian cancer in the general population, but may be part of monitoring in high-risk individuals.

There is no special preparation needed for the HE4 test. It’s recommended to follow your normal routine.

If your HE4 levels are elevated, it is advisable to consult an oncologist, a doctor who specializes in cancer.

While the HE4 test is primarily used to monitor ovarian cancer, it may also be used in some cases to monitor certain types of lung cancer.

Both HE4 and CA-125 are used as tumor markers for ovarian cancer. However, CA-125 is more commonly used while HE4 is considered more specific for ovarian cancer.

If the HE4 test results are abnormal, additional tests and diagnostic procedures may be recommended by your healthcare provider to evaluate the cause of elevated levels.

Coverage for the HE4 test may vary depending on your health insurance plan. It’s best to contact your insurance provider to determine if the test is covered.

The HE4 test is not definitive on its own and should be used in conjunction with other tests and clinical evaluation. Additionally, other benign conditions can cause elevated HE4 levels.

The HE4 test plays an important role in the management of ovarian cancer, particularly in monitoring the disease. Understanding the purpose of the test and what the results may indicate is crucial for patients and their families. As with all tests, it is important to discuss the results and any subsequent steps with your healthcare provider. Your healthcare team is the best resource for information on how the HE4 test fits into your overall treatment and monitoring plan.