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Homovanillic Acid (HVA) - Random Urine

Homovanillic acid (HVA) is a breakdown product of dopamine, a chemical that transmits signals in the brain and other vital areas. The homovanillic acid urine test is used primarily to evaluate the functioning of the adrenal glands, specifically to detect neuroblastomas in children. Neuroblastoma is a type of cancer that forms in certain types of nerve tissue and is most often found in the adrenal glands, which are positioned on top of the kidneys.

This test measures the quantity of homovanillic acid in the urine, typically over a 24-hour period. Since the levels of HVA can vary throughout the day, collecting urine over a 24-hour period can give a more accurate indication of average HVA production


  • Test Name Homovanillic Acid (HVA) - Random Urine
  • Sample Type Urine
  • Preparations Required There are no specific instructions to prepare for this test. It is always a good idea to stay hydrated, but drinking excessive amounts of water is not necessary
  • Report Time 5 days

Why is this test done?

This test is primarily used to detect neuroblastomas in children, which are types of tumors that often start in the adrenal glands.

What kind of sample is needed for this test?

A urine sample is required for this test. It's often collected over a 24-hour period to give a more accurate representation of HVA levels.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports
Frequently Asked Questions

No, fasting is not required before this test.

This test is typically done when a healthcare provider suspects a neuroblastoma or to monitor the effectiveness of treatment if a neuroblastoma has been diagnosed.

Normal values can vary depending on the lab, but generally, the normal range for HVA in a 24-hour urine sample is less than 8 mg per day for adults, and less than 15 mg per day for children.

Medications, stress, and exercise can potentially affect the levels of HVA. It's important to tell your healthcare provider about any medications you are taking.

Elevated levels of HVA can be a sign of a neuroblastoma or other type of tumor. If your levels are high, your healthcare provider will likely order additional tests.

If your HVA levels are abnormal, you should see a specialist like an endocrinologist or oncologist.

No, this test requires a laboratory to measure the amount of HVA in a urine sample. You can collect the sample at home, but it must be analyzed in a laboratory.

Other tests that might be done include a VMA (vanillylmandelic acid) test and catecholamines test, both of which also help detect tumors in the adrenal glands.

Yes, certain medications can affect the results of this test. Make sure to tell your doctor about any medications you are taking.

Dopamine is a type of neurotransmitter, which is a chemical messenger in the brain. It plays roles in how we feel pleasure and our ability to think and plan.

Neuroblastoma is a type of cancer that forms in certain types of nerve tissue. It frequently starts from one of the adrenal glands but can also develop in nerve tissue along the spine, chest, abdomen, or pelvis.

This test is a simple urine test, so it does not pose any significant risks.

High levels of HVA are often associated with certain types of tumors, so prevention is not usually possible. However, regular check-ups and tests can help catch these tumors early when they are easier to treat.

The test works by measuring the amount of homovanillic acid, a breakdown product of dopamine, in your urine. High levels can indicate the presence of a neuroblastoma or other disorders.

The turnaround time for the test is typically 5-7 days, but it can vary depending on the laboratory.

While diet generally does not significantly affect the test, consuming large quantities of foods containing vanillin, a compound similar to homovanillic acid, may interfere with the test. Such foods include vanilla extract and vanilla-flavored foods.

The urine sample is usually collected over a 24-hour period. You will be given a special container to collect your urine in and specific instructions on how to collect the sample.

If your test results are abnormal, it's important to discuss them with your healthcare provider. They can explain what the results might mean and guide you on the next steps.

Yes, this test can be done on individuals of all ages, including infants and children. It is often used to detect neuroblastomas, a type of cancer that usually affects children.

Yes, you can carry on with most of your normal activities. However, it's recommended that you avoid vigorous exercise, as it might affect the test results.

During the collection period, it's important to keep the sample refrigerated or on ice. This helps to preserve the substances in the urine that are being measured.

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