HLA-B7 is a specific variant of the Human Leukocyte Antigen (HLA) - a protein found on the surface of white blood cells that plays a crucial role in immune response. Different HLA variants are associated with different conditions, and HLA-B7 is often seen in patients with certain types of seronegative spondyloarthropathies, a group of diseases causing inflammatory arthritis affecting the spine and other joints.
The HLA-B7 test identifies the presence of the specific HLA-B7 variant in your body. However, not everyone who tests positive for HLA-B7 will develop seronegative spondyloarthropathy, and conversely, not everyone with sero negative spondyloarthropathy will test positive for HLA-B7. Nonetheless, this test holds significance in diagnosing and planning treatments for those who are HLA-B7 positive or negative.
Sprint Diagnostics provides affordable HLA B7 testing at your nearest locations in Hyderabad.
The HLA B7 test is utilized for the detection of individuals with seronegative spondyloarthropathy, juvenile spondyloarthropathy, and certain instances such as Undifferentiated Spondyloarthropathy.
Seronegative spondyloarthropathies are a group of inflammatory joint diseases that primarily affect the spine, though other joints can also be involved. The term "seronegative" refers to the fact that these conditions test negative for rheumatoid factor, a protein often found in other types of arthritis.
HLA-B7, a form of human leukocyte antigen, is associated with ankylosing spondylitis, reactive arthritis, and juvenile rheumatoid arthritis. It serves as a genetic marker rather than a conclusive determinant, impacting the vulnerability to these autoimmune disorders. This underscores the intricate nature of disease progression, which involves a combination of genetic and environmental factors.
A positive result indicates the presence of the HLA-B7 variant. However, this does not definitively diagnose a seronegative spondyloarthropathy, as not everyone with this variant will develop these conditions. A negative result means the HLA-B7 variant was not detected.
The price of HLA B7 test in Hyderabad is just ₹5500 at Sprint Diagnostics near your locations.