FISH for PDGFR B Test - Price, Normal Range | Sprint Diagnostics Hyderabad

Q: What is the FISH for PDGFR-B test used for?

The FISH for PDGFR-B test is used to detect rearrangements of the PDGFR-B gene. This can help in the diagnosis and monitoring of certain types of leukemia and myeloproliferative disorders.

Q: Who should consider taking this test?

Individuals who have symptoms or blood test results that suggest leukemia or a myeloproliferative disorder, as well as those who have already been diagnosed and need monitoring, may be advised to take this test.

Q: Can medication affect the result of the test?

Yes, certain medications might affect the results. It is important to tell your doctor about any medications or supplements you are taking.

Fluorescence In Situ Hybridization (FISH) for PDGFR-B is a diagnostic test that looks for genetic abnormalities involving the Platelet-Derived Growth Factor Receptor Beta (PDGFR-B) gene. PDGFR-B is a gene that encodes for a cell surface receptor, which plays a crucial role in cell signaling pathways that regulate cell growth, division, and development. In particular, this receptor is important for the development of blood vessels and the migration of cells within the body. However, when abnormalities occur, such as rearrangements involving the PDGFR-B gene, it can lead to various diseases including certain types of leukemia and other disorders.

Understanding the genetic profile of an individual can provide important information for the diagnosis, prognosis, and treatment planning of diseases. The FISH for PDGFR-B test specifically looks for rearrangements of the PDGFR-B gene which may be associated with various hematological disorders.

Test NameFISH for PDGFR – B (Platelet Derived Growth Factor Receptor – beta)
Sample TypeBlood or Bone Marrow
Preparations RequiredNo specific preparation is required.
Report Time5 days

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Frequently Asked Questions

What is the FISH for PDGFR-B test used for?

A sample of blood or bone marrow is taken from the patient. The sample is then processed in a laboratory where special probes are used to visualize the PDGFR-B gene under a microscope.

Who should consider taking this test?

No special preparation is needed for the FISH for PDGFR-B test.

What does a positive result mean?

A negative result suggests that there is no detectable rearrangement involving the PDGFR-B gene in the analyzed cells.

Can medication affect the result of the test?

The test itself has very few risks and is similar to having blood drawn for routine testing. However, bone marrow biopsy, if required, can cause discomfort and has slightly more risks.

Is the test conclusive for diagnosing a disease?

Lifestyle choices such as diet, exercise, and exposure to environmental toxins can potentially affect the expression of PDGFR-B. Medication can also modify its activity.

What are the non-modifiable factors that affect PDGFR-B?

The frequency of testing varies depending on the underlying condition and the doctor’s recommendation.

What are the normal values for this test?

If you have abnormal results, you should consult a hematologist or oncologist as they specialize in blood disorders and cancers.

Is FISH for PDGFR-B used in research?

Yes, FISH for PDGFR-B is also used in research settings to understand the role of PDGFR-B in different diseases and to develop new therapies.

It's important to remember that while genetic testing can provide valuable information, the interpretation and management of test results should be performed by a healthcare professional. Understanding the genetic aspects of blood disorders can be an essential component of personalized medicine and tailored treatment strategies. However, it is just one part of a comprehensive approach to managing these complex conditions. Discuss the results and the best course of action with your doctor to make well-informed healthcare decisions.

FISH for PDGFR ? B (Platelet Derived Growth Factor Receptor ? beta)

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FISH for PDGFR – B (Platelet Derived Growth Factor Receptor – beta)

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