Estradiol (E2)

High levels of estradiol in women could indicate early puberty, tumors, or abnormal functioning of the ovaries or adrenal glands. In men, high levels could indicate feminization, which could be due to conditions like liver disease, a tumor, or drug abuse. Low levels in women could suggest menopause, poor ovarian function, or anorexia nervosa, while in men, it could suggest a decrease in testicular function.

In women, symptoms might include irregular or absent periods, hot flashes, mood swings, vaginal dryness, or difficulty getting pregnant. In men, symptoms might include gynecomastia, infertility, or sexual dysfunction.

The risks associated with a blood draw are minimal, including slight pain or bruising at the site of the needle prick.

Yes, certain medications can affect estradiol levels. These include hormonal contraceptives, hormone therapy, antibiotics, and certain psychiatric medications.

No special preparation is needed for the estradiol test.

Yes, even though estradiol is commonly thought of as a female hormone, it is important for men as well. It helps regulate libido, erectile function, and the production of sperm.

Yes, estradiol plays a key role in the regulation of the menstrual cycle and the development of eggs in the ovaries. It is also important for maintaining pregnancy.

Yes, estradiol levels can fluctuate throughout the day, and in women, they can also vary throughout the menstrual cycle.

Normal levels depend on your sex, age, and for women, the stage of the menstrual cycle. The lab report will usually provide a reference range.

Factors that can affect estradiol levels include age, sex, medications, health of your ovaries or testes, and overall health.

Yes, obesity, alcohol consumption, and having a diet high in phytoestrogens (found in foods like soy) can affect estradiol levels.

Yes, estradiol can affect mood, particularly in women. Some women may experience mood swings, anxiety, or depression due to fluctuating estradiol levels during their menstrual cycle or menopause.

If your estradiol levels are abnormal, you should consult your primary care doctor, who may refer you to an endocrinologist or a gynecologist if you are a woman.

Monitoring and understanding estradiol levels can be essential for both women and men, especially those dealing with fertility issues, hormonal imbalances, or transitioning into menopause. It is important to interpret the results in conjunction with other tests and clinical evaluations, and to discuss them thoroughly with your doctor to ensure appropriate medical guidance and care.