Dysmorphic Red Blood Cells, commonly referred to as Dysmorphic RBCs, are abnormal forms of red blood cells that can be found in urine. Their presence is typically an indication of a problem within the kidneys, such as glomerulonephritis, which is an inflammation of the glomeruli. The glomeruli are tiny clusters of blood vessels within the kidneys that are responsible for filtering the blood and creating urine.
Normal RBCs are round, but when they pass through the diseased glomeruli, they undergo shape changes and become dysmorphic. Therefore, the detection of dysmorphic RBCs in urine is significant in the evaluation of hematuria (blood in the urine) and helps in identifying the source of bleeding within the urinary tract.
The presence of Dysmorphic RBCs in urine is indicative of a glomerular disorder, which means there might be a problem with the kidneys' filtration system.
A midstream urine sample is typically collected. This means you urinate a small amount into the toilet before collecting a sample in a sterile container. This helps to ensure that the sample is not contaminated with bacteria or cells from the outside of the urinary tract.
Normal RBCs are smooth and round, while Dysmorphic RBCs have irregular shapes due to damage as they pass through diseased glomeruli in the kidneys. The presence of normal RBCs in urine might indicate bleeding in the lower urinary tract, while dysmorphic RBCs suggest a kidney problem.
While not always indicative of a serious issue, the presence of Dysmorphic RBCs should be evaluated further to rule out kidney diseases, especially if there are other signs or symptoms such as protein in the urine, swelling, or high blood pressure.
Certain medications and foods can cause discoloration of the urine or affect the urinary tract. It's important to tell your doctor about any medications you are taking or foods you have consumed.
Conditions such as glomerulonephritis, lupus nephritis, vasculitis, or IgA nephropathy can cause Dysmorphic RBCs to appear in the urine.
Hematuria is the presence of blood in the urine. When the blood in urine is due to a kidney problem, Dysmorphic RBCs are often present.
Symptoms of kidney problems include swelling of the legs, decreased urine output, fatigue, shortness of breath, and high blood pressure.
Typically, Dysmorphic RBCs are not present in the urine of healthy individuals. Their presence is usually indicative of some underlying kidney issue.
Treatment depends on the underlying cause. In cases of glomerulonephritis or another kidney disorder, medications such as corticosteroids may be prescribed. It's important to manage blood pressure and follow a kidney-friendly diet as well.
If the test results show Dysmorphic RBCs in the urine, its important to consult your doctor for further evaluation and to determine the underlying cause.
Not usually. It is typically done when there is a suspicion of kidney disease, especially if there are symptoms like blood in the urine.
Yes, the presence of Dysmorphic RBCs can be an early indicator of kidney disease, especially glomerular diseases.
Factors might include infections, autoimmune diseases, certain medications, and genetic predispositions.
If your test results are abnormal, it is advisable to consult your primary care doctor who might refer you to a nephrologist for specialized kidney care.
The presence of Dysmorphic RBCs in urine is vital in assessing kidney health. The test can provide essential insights for a doctor to evaluate the state of a patient's kidneys and urinary tract. Early detection and management of any underlying disease are crucial for preventing progressive kidney damage. It's essential for patients to communicate openly with their doctors and follow recommended treatment plans.