C-Peptide Stimulation by Glucagon Test

The test is used to evaluate the ability of the pancreas to produce insulin, which is vital in the management of diabetes and in assessing the pancreas before surgery.

After fasting, you will have blood drawn to measure baseline C-Peptide levels. Glucagon will be injected, and blood samples will be taken at intervals to measure C-Peptide levels.

Glucagon is a hormone that increases blood sugar levels. It is injected to stimulate the pancreas to produce insulin, and subsequently, C-Peptide, which is measured in the blood samples.

You should fast for 8-10 hours before the test. Consult your doctor for any specific instructions regarding your medications or health condition.

Higher levels of C-Peptide after glucagon stimulation indicate that the pancreas is producing insulin, whereas low levels suggest inadequate insulin production. Your doctor will interpret the results based on your medical history and other test results.

The normal ranges for C-Peptide levels can vary depending on the laboratory. Generally, the normal range for fasting C-Peptide levels is around 0.8 to 3.1 ng/mL.

Yes, in Type 1 diabetes, C-Peptide levels tend to be low because the body doesn't produce enough insulin. In Type 2 diabetes, C-Peptide levels may be normal or high as the body produces insulin but doesn't use it effectively.

The risks are minimal but include discomfort or bruising at the needle site. In rare cases, a person may have an allergic reaction to glucagon.

The frequency of this test depends on your health condition and your doctor’s recommendations.

You should consult an endocrinologist or your primary care doctor for guidance and management.

Factors affecting C-Peptide levels include kidney function, medications, and the timing of the test in relation to meals.

Discuss with your doctor whether you should continue taking your regular medications before the test.

Besides diabetes, this test can be used in cases of insulinoma (a tumor of the insulin-producing cells in the pancreas) and to assess pancreatic function before surgery.

The C-Peptide Stimulation by Glucagon Test involves injecting glucagon to stimulate the pancreas, whereas the C-Peptide blood test measures the C-Peptide levels at a single point in time without stimulation.

Some studies suggest that high C-Peptide levels may be associated with an increased risk of heart disease, but more research is needed.

The C-Peptide Stimulation by Glucagon Test is a valuable tool in evaluating pancreatic function, particularly in the context of diabetes management and surgical assessment of the pancreas. The test involves fasting, followed by glucagon injection, and multiple blood draws to measure C-Peptide levels. Understanding your C-Peptide levels is crucial in managing diabetes and maintaining overall health. Consult your doctor for specific preparation instructions and interpretation of results.