Anti-Thyroid Peroxidase (Anti-TPO) antibodies are proteins produced by the immune system that mistakenly attack the thyroid gland, specifically an enzyme called thyroid peroxidase. Thyroid peroxidase plays a key role in the production of thyroid hormones. The Anti-TPO antibody test measures the level of these antibodies in the blood.
This test is critical for evaluating thyroid function and diagnosing autoimmune thyroid disorders such as Hashimoto's thyroiditis and Graves' disease. Thyroid peroxidase antibody test can also be helpful in determining the cause of other thyroid problems, including an enlarged thyroid (goiter) or thyroid nodules.
The TPO Antibodies Test is a blood test that measures the levels of anti-thyroid peroxidase antibodies in the blood. Elevated levels of Anti-TPO indicate that the body's immune system is attacking the thyroid gland.
A healthcare professional will draw a blood sample from your arm. The sample is then sent to a laboratory for analysis.
Elevated levels of Anti-TPO antibodies may indicate an autoimmune thyroid disorder such as Hashimoto's thyroiditis or Graves' disease. It can also suggest a general tendency toward autoimmune disorders.
The normal range can vary between laboratories, but generally, levels below 35 IU/mL are considered normal.
Symptoms can vary and may include fatigue, weight gain, feeling cold, dry skin, hair loss, and depression in the case of Hashimoto’s, or anxiety, heat sensitivity, weight loss, and bulging eyes in the case of Graves’ disease.
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