Anti-Thrombin (AT III) Activity - Functional

A healthcare professional will take a blood sample from a vein in your arm. The sample is then sent to a laboratory where the activity of the anti-thrombin protein is measured.

A doctor might order this test if you have a family history of clotting disorders, unexplained blood clotting, recurrent miscarriages, or if you are on anticoagulant therapy.

Low levels of Anti-Thrombin activity may indicate an inherited deficiency or an acquired condition that reduces the protein's levels or function. This can increase the risk of blood clots.

High levels are less common but might be associated with a low risk of clotting. This can be due to various factors including certain medications or liver dysfunction.

Normal ranges can vary, but generally, AT III activity levels between 80% and 120% are considered normal.

No special preparation is needed for the test, but you should inform your doctor about any medications or supplements you are taking.

The frequency of this test depends on your health status and history. Your doctor will recommend how often you should have this test based on your specific situation.

The risks associated with this blood test are minimal and include slight pain or bruising at the site where the needle was inserted.

Yes, certain medications such as heparin, oral anticoagulants, and hormone replacement therapy can affect the results of this test. Inform your doctor of any medications you are taking.

Anti-Thrombin activity tests measure how well the protein is functioning, while Anti-Thrombin antigen tests measure the amount of the protein in the blood.

Modifiable factors include medication use, diet, and lifestyle. For instance, vitamin K intake can affect clotting factors, and lifestyle changes like exercise can affect coagulation.

Non-modifiable factors include genetics and certain medical conditions that affect the liver or kidneys.

If your Anti-Thrombin activity levels are abnormal, it is advisable to consult a hematologist or your primary care doctor for further evaluation and guidance.

Yes, Anti-Thrombin activity levels can change during pregnancy. If you are pregnant and have a history of clotting disorders, your doctor may monitor your Anti-Thrombin levels closely.

Understanding your Anti-Thrombin activity levels can be critical in managing your health, especially if you are at risk for clotting disorders. Regular monitoring and adherence to your doctor’s advice are vital. This test is a valuable tool that can provide your doctor with information necessary for the diagnosis and management of blood clotting disorders.