Anti Human Tissue Transglutaminase (tTG) Antibody (IgA) test, also known as the tTG-IgA test, is an essential diagnostic tool for diagnosing celiac disease, an autoimmune condition caused by gluten ingestion. The amount of IgA antibodies against tissue transglutaminase (tTG), an enzyme involved in protein metabolism, is measured in this test.
Doctors may prescribe tTG-IgA test, if a child shows the symptoms of celiac disease, such as poor growth, stomach pain, constipation, diarrhea, vomiting, or rashes. The test may also be recommended if a child has a condition that increases their risk of celiac disease, such as type 1 diabetes, thyroid problems, or a family member with celiac disease.
The normal range for tissue transglutaminase iga is an important reference point in test interpretation, however a negative result for tissue transglutaminase ab iga may provide vital information concerning the absence of celiac-related antibodies.
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Anti Human tTG (IgA) test is important because it measures the level of IgA antibodies against tTG in your blood and helps in diagnosing celiac disease. Early detection can prevent complications such as malnutrition, osteoporosis, infertility, and certain types of intestinal cancer.
If your Anti Human tTG (IgA) test is positive, you should consult with a gastroenterologist, a doctor specializing in the digestive system, for further evaluation and treatment.
While high levels of Anti Human tTG (IgA) are most commonly associated with celiac disease, they can also be present in other autoimmune conditions.
The frequency of the Anti Human tTG (IgA) test depends on your health condition and the advice of your healthcare provider. If you have celiac disease, you should undergo regular testing to check your response to a gluten-free diet.
The results of Anti Human tTG (IgA) test will be interpreted by the doctor treating you based on your symptoms, medical history, and other relevant testing. Anti Human tTG (IgA) antibodies may indicate celiac disease, however more testing may be required to confirm the diagnosis.