Alpha Feto Protein (AFP) - Amniotic Fluid Test - Price, Normal Range | Sprint Diagnostics Hyderabad

Measuring AFP levels in amniotic fluid is primarily used for the detection of certain birth defects, such as neural tube defects (e.g., spina bifida or anencephaly) and abdominal wall defects. It may also be elevated in other conditions such as fetal distress or death.

This test is performed on a sample of amniotic fluid. The fluid is obtained through a procedure known as amniocentesis, where a needle is inserted through the abdominal wall into the uterus, and a small amount of amniotic fluid is withdrawn.

A healthcare provider might order an AFP test on amniotic fluid if a pregnant woman is at increased risk for having a baby with a birth defect. This could be due to advanced maternal age, a family history of birth defects, or if a previous child was born with a birth defect.

Results are typically reported in concentration (like micrograms per milliliter). A standard range for AFP in amniotic fluid is approximately 0.5 to 2.0 mg/dL. Elevated levels can indicate certain types of birth defects, whereas very low levels of AFP can suggest other conditions, such as Down's syndrome.

AFP levels can vary depending on the gestational age of the fetus. It can also be affected by factors such as the presence of more than one fetus, errors in estimating the gestational age, and certain maternal conditions like diabetes.

High levels of AFP in amniotic fluid can suggest the presence of certain birth defects in the fetus, such as neural tube defects or abdominal wall defects. It may also indicate fetal distress or death.

Amniocentesis is generally a safe procedure, but it does carry a small risk of complications. These may include leakage of amniotic fluid, miscarriage, needle injury to the baby, or infection.

There's no special preparation required for an AFP test. However, because it involves an invasive procedure (amniocentesis), you should discuss the benefits and risks with your healthcare provider.

If AFP levels are abnormal, additional testing may be recommended to confirm a diagnosis or to look for other genetic or chromosomal abnormalities. This may include ultrasound imaging or other specialized genetic tests.

If your AFP levels are abnormal, your healthcare provider may order additional tests to help determine the cause. This could include ultrasounds, genetic counseling, or possibly more invasive diagnostic procedures.

Most medications do not interfere with the test, but some medications can affect the level of proteins in your blood. It's important to discuss all medications you're taking with your healthcare provider before the test.

No, AFP levels in amniotic fluid cannot predict the gender of the baby. The test is used to detect certain birth defects, not to determine the sex of the baby.

Other tests often performed in conjunction with AFP testing include human chorionic gonadotropin (hCG), estriol, and inhibin-A. Together, these tests form part of what's known as a quadruple screen.

The AFP test is typically only performed once during a pregnancy, between the 15th and 20th week. Your healthcare provider will recommend when you should have this test based on your symptoms, medical history, and whether you're monitoring a known condition.