Alanine aminotransferase (ALT), also known as serum glutamic-pyruvic transaminase (SGPT), is an enzyme found primarily in the liver and kidneys. The ALT test measures the amount of this enzyme in the blood, and it is used to determine if there is damage to the liver.
Liver damage releases ALT into the bloodstream, causing levels to rise. Therefore, an ALT test can help identify liver diseases like hepatitis or cirrhosis, or conditions like jaundice. It can also monitor the effectiveness of treatments for liver disease and measure the extent of damage caused by diseases such as alcohol-related liver disease.
It's also used to monitor the progression of a disease and the effectiveness of treatments.
Fasting is not typically required for this test, but it might be performed as part of a series of tests that do require fasting.
Your doctor may recommend an ALT test if you have symptoms suggestive of liver disease, such as jaundice (yellowing of the skin and eyes), dark urine, nausea, vomiting, and abdominal pain.
The ALT test measures the level of alanine aminotransferase, an enzyme found primarily in the liver, in your blood.
The frequency of this test depends on your health condition. Your doctor will advise you based on your specific circumstances.
Normal ALT levels generally range from 7 to 56 units per liter (U/L), but this range can vary depending on the lab.
There are no specific precautions related to the test itself. However, if you have liver disease or damage, you should follow your doctor's advice regarding diet, medication, and lifestyle modifications.
Factors affecting ALT levels can include liver diseases, alcohol consumption, certain medications, and conditions like celiac disease, mononucleosis, or heart attack.
Modifiable factors include alcohol consumption, medication use, and managing any underlying conditions affecting the liver. Non-modifiable factors include genetic predisposition to certain liver conditions.
In case of abnormal results, you should consult a hepatologist or a gastroenterologist for further investigation and management.
No specific preparation is needed for this test, but you should inform your doctor about any medications or supplements you are taking.
Yes, the test results can vary slightly between labs due to differences in equipment, techniques, and chemicals used.
The test itself does not pose any significant risk. However, as with any blood draw, there is a minimal risk of bruising, bleeding, or infection at the site of the needle insertion.
A blood sample is taken by inserting a needle into a vein in your arm. The blood is then sent to a lab for analysis.
High ALT levels themselves do not cause symptoms, but they can be indicative of underlying liver disease. Symptoms of liver disease can include jaundice, fatigue, nausea, vomiting, abdominal pain, and itching.
The ALT test is a useful tool for identifying liver damage and disease. Regular monitoring and discussions with your doctor can ensure timely diagnosis and appropriate management of conditions that might be causing elevated ALT levels.