The SLE Panel is a group of tests used in the diagnosis and monitoring of Systemic Lupus Erythematosus (SLE), an autoimmune disease where the immune system attacks healthy tissue. This panel includes ANA (Antinuclear Antibodies) - IFA, Anti-dsDNA (Anti-double-stranded DNA) - IFA, Anti-ssDNA (Anti-single- stranded DNA), Sm (Smith) Antibodies, U1RNP (U1-Ribonucleoprotein) Antibodies, CRP (C-reactive protein), and Histone Antibodies.
The SLE Panel is performed to help diagnose SLE in individuals presenting with symptoms indicative of the disease such as joint pain, fatigue, rash, and fever. It is also used to monitor disease progression and response to treatment in diagnosed individuals.
No, fasting is not required before the SLE Panel.
Note: Home Sample Collection is only for Pathology lab tests.
The SLE Panel measures the levels of several different antibodies in your blood that are often elevated in people with SLE, as well as CRP, a marker of inflammation.
This test is typically performed when SLE is suspected and may be repeated to monitor disease progression or response to treatment.
Normal results would typically indicate no or low levels of the tested antibodies. However, normal ranges can vary between labs.
There are no specific precautions to take before or after the test. However, it's important to inform your doctor of any medications you're taking as they could influence the results.
No. The production of these antibodies is an immune response and is not directly influenced by lifestyle factors.
Genetic factors and underlying autoimmune conditions can influence the production of these antibodies.
You should consult with your doctor who may refer you to a rheumatologist for further evaluation and treatment if the results show elevated levels of these antibodies.
The test involves a standard blood draw, which carries minimal risks such as slight pain, bruising, or infection at the puncture site.
Yes, other autoimmune disorders and certain infections can also cause elevated levels of these antibodies.
Certain medications, such as antibiotics and anti-inflammatory drugs, could potentially affect the levels of these antibodies.
A positive result indicates the presence of these antibodies in your blood, suggesting you may have SLE or another autoimmune condition.
There's no way to influence the production of these antibodies. However, managing any diagnosed autoimmune conditions and maintaining a healthy lifestyle can help manage symptoms.
Treatment for SLE often involves medications to manage symptoms, slow disease progression, and reduce inflammation. Treatment plans are individualized and depend on the severity of your condition and your specific symptoms
Yes, individuals presenting with symptoms of SLE or those with a family history of autoimmune disorders are more likely to test positive
No specific preparation is needed. However, always inform your doctor about any symptoms and all medications or supplements you're taking.
Consistently elevated levels of these antibodies could indicate active SLE or other autoimmune condition, which requires ongoing management
The SLE Panel is quite reliable but not definitive. Additional tests may be needed to confirm a diagnosis of SLE
Your doctor may order other tests such as kidney function tests, complete blood count, and erythrocyte sedimentation rate (ESR) to better understand your condition
thorough understanding of the SLE Panel can support a more informed conversation with your doctor about your health. If you have concerns or questions, be sure to address them with your doctor who can provide you with the most accurate and helpful information