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Lab Test

Lung Cancer Panel 3

Lung Cancer Panel 3 is a specialized test employed to identify genetic alterations linked with non-small cell lung cancer (NSCLC), specifically EGFR mutations, ALK rearrangements, and ROS1 rearrangements. These genetic changes, although less common, can significantly influence the disease course and treatment approach.


  • Profile Name Lung Cancer Panel 3
  • Sample Type Tissue
  • Preparations Required There are no specific instructions needed for this test.
  • Report Time 3 Days

EGFR mutations are identified through a technique known as Amplification Refractory Mutation System (ARMS) Polymerase Chain Reaction (PCR). This is a highly specific and sensitive method that can detect even minor amounts of mutated DNA in a sample. Alterations in the ALK and ROS1 genes are detected through Fluorescence In Situ Hybridization (FISH), which allows for the visualization of specific regions on the chromosomes where these genes are located.

This comprehensive panel is a crucial aspect of personalized cancer treatment, providing information that can guide the selection of targeted therapies and contribute to a more tailored and potentially effective treatment strategy.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports

Note: Home Sample Collection is only for Pathology lab tests.

Frequently Asked Questions

This test is important as it identifies specific genetic changes that can influence the development and progression of your cancer. The information gathered can help your doctor create a more personalized treatment plan.

A tissue sample is usually obtained from a biopsy of the tumor. The method of obtaining the sample depends on the size and location of the tumor.

There are no special preparations required for this test. However, if anesthesia is needed for the biopsy, you may need to fast before the procedure.

The results typically take 1 to 2 weeks, although this can vary depending on the laboratory.

If your results indicate a mutation or rearrangement in the EGFR, ALK, or ROS1 genes, you might benefit from targeted therapies that specifically inhibit these genetic changes. Your doctor will discuss the implications of your results and the potential treatment options.

The risks are primarily associated with the biopsy procedure rather than the test itself. These might include infection, bleeding, and complications from anesthesia.

A negative result means that none of the genetic changes tested for were detected in your tumor. However, this does not imply that your cancer is untreatable. Other forms of treatment, such as chemotherapy or radiation, may still be effective.

While this test provides important information for treatment selection, it's not typically used for treatment monitoring. Other tests, like imaging studies or blood tests, are usually utilized for this purpose.

Yes, unless you are required to fast for the biopsy procedure.

The turnaround time is typically 1 to 2 weeks, but this may vary based on the laboratory.

If no genetic changes are detected, it simply means that other forms of treatment may be more suitable for your type of cancer.

This test is usually ordered by a healthcare provider managing your care. It's recommended to discuss your questions or concerns with them.

Coverage for this test can vary by insurance provider and policy. You should check with your insurance company for specific information regarding coverage.

Mutations or rearrangements in these genes can drive the growth and spread of cancer cells. Targeted therapies aimed at these genetic changes can often be more effective and have fewer side effects than traditional chemotherapy.

This test is typically performed at the time of diagnosis or when there is a change in the disease state. However, the frequency can depend on many factors, including your specific type of cancer and response to treatment. Always consult with your healthcare provider for personalized advice.

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