Pathologists employ immunohistochemistry (IHC) as a vital diagnostic tool for sarcomas along with other cancers. Sarcomas are a wide variety of cancers that originate in the soft tissues and bones. Pathologists are able to correctly identify and classify these malignancies with the use of an IHC Sarcoma Panel test, which uses a series of markers such as Vimentin, SMA, Desmin, Myogenin, S100, CD34, CD31, CKIT, Caldesmon, NSE, CD 99, FLI1, AE1/3, CK, EMA, and TLE-1. This test is useful in determining the origin tissue, distinguishing between subtypes, and developing an accurate treatment strategy.
When there is a possibility of a soft tissue tumour based on the patient's symptoms, imaging results, or an initial biopsy report, the IHC Sarcoma Panel Test is frequently requested. Since sarcomas can arise from a variety of cell types, its goal is to identify particular proteins (antigens) in the tissue sample that are connected to distinct cell types. A range of markers, each representing a distinct cell type, make up the panel.
At Sprint Diagnostics, our experienced pathologists will use advanced technology to diagnose the Sarcomas. In the IHC sarcoma panel test we offer, it can help differentiate between various sarcoma subtypes, which have different treatment approaches and prognoses. Sprint Diagnostics offers this test at an affordable price with home sample collection and you can download the reports online
Note: Home Sample Collection is only for Pathology lab tests.
An IHC Sarcoma Panel utilizes a set of markers, including Vimentin, SMA, Desmin, Myogenin, S100, CD34, CD31, CKIT, Caldesmon, NSE, CD 99, FLI1, AE1/3, CK, EMA, and TLE-1, to help pathologists identify and classify these cancers more accurately.
A positive test result means that the tissue sample has tested positive for one or more of the markers included in the panel, which helps to identify the type of sarcoma.
Sarcomas are a diverse group of cancers that start in the bones and soft tissues. An IHC Sarcoma Panel utilizes a set of markers, including Vimentin, SMA, Desmin, Myogenin, S100, CD34, CD31, CKIT, Caldesmon, NSE, CD 99, FLI1, AE1/3, CK, EMA, and TLE-1, to help pathologists identify and classify these cancers more accurately.
This test provides information about the specific proteins present in the tissue sample, helping to identify the cell type from which the tumour originated and distinguish between different sarcoma subtypes.
The 'normal' values for this test are not straightforward because it is not a quantitative test. It is about whether specific markers are present (positive) or absent (negative), helping to indicate the type of sarcoma.