When it comes to understanding and mitigating the risk of hereditary cancers, the Hereditary Cancer Gene Panel-Focused stands out as an advanced genetic test. This test explicitly identifies mutations in a carefully selected panel of genes associated with an elevated risk of developing specific types of cancer. Utilizing cutting-edge next-generation sequencing (NGS) technology, the test meticulously analyzes the patient's DNA, typically obtained through a blood sample.
For individuals seeking comprehensive insights into their genetic predisposition to cancer, hereditary cancer gene panel testing provides a targeted and thorough examination. This focused approach is designed to unveil potential genetic markers linked to cancer susceptibility, empowering individuals and their healthcare providers with valuable information for proactive health management.
The hereditary cancer panel test offers a streamlined yet comprehensive solution for those looking to assess their genetic risk factors. By concentrating on a specific set of genes associated with hereditary cancers, this test provides a nuanced understanding of an individual's predisposition to particular cancer types.
The hereditary gene panel and hereditary cancer gene panel are integral components of the genetic testing landscape, offering tailored insights that can guide personalised monitoring plans and preventive measures.
This specific panel examines numerous genes, including but not limited to AIP, ALK, APC, AR, ATM, BAP1, BARD1, BLM, BMPR1A, BRCA1, BRCA2, BRIP1, BUB1B, CD82, CDC73, CDH1, CDK4, CDKN1C, CDKN2A, CEBPA, CEP57, CHEK2, CYLD, DDB2, DICER1, DIS3L2, EGFR, ELAC2, ENG, EPCAM, ERCC2, ERCC3, ERCC4, ERCC5, EXT1, EXT2, EZH2, FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, FH, FLCN, GATA2, GPC3, HRAS, KIT, MAX, MEN1, MET, MLH1, MLH3, MRE11A, MSH2, MSH3, MSH6, MSR1, MUTYH, MXI1, NBN, NF1, NF2, NSD1, PALB2, PHOX2B, PMS1, PMS2, PRF1, PRKAR1A, PTCH1, PTEN, RAD50, RAD51C, RAD51D, RB1, RECQL4, RET, RHBDF2, RNASEL, RUNX1, SBDS, SDHAF2, SDHB, SDHC, SDHD, SLX4, SMAD4, SMARCB1, STK11, SUFU, TGFBR2, TMEM127, TP53, TSC1, TSC2, VHL, WRN, WT1, XPA, XPC.
Note: Home Sample Collection is only for Pathology lab tests.
This focused Hereditary Cancer Gene Panel screens for mutations in a broad range of genes known to be associated with an increased risk of various types of cancer.
This test is usually recommended for individuals who have a strong family history of certain cancers or who have a known mutation in their family. It's also suitable for individuals diagnosed with cancer at a younger age than typically expected or those with multiple primary cancers.
This test is typically performed using a blood sample. However, in certain circumstances, saliva or another type of body fluid/tissue may be used. DNA is extracted from the sample and analyzed using next-generation sequencing (NGS) to identify mutations in the specified genes.
Yes. This test may provide insights into the genetic cause of your cancer, which can sometimes influence treatment decisions. Furthermore, knowing that a hereditary mutation is present can provide useful information for family members who may also be at increased risk.
Some genetic mutations identified by this test can influence treatment decisions. For example, certain mutations in the BRCA1 or BRCA2 genes may make a person more likely to respond to specific types of chemotherapy or targeted therapies.