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Lab Test

Anti- Ganglioside Antibodies IGG

The Ganglioside - IgG Antibody Panel by Immunoblot is a test performed to identify the presence of IgG antibodies against gangliosides in the blood. Gangliosides are complex molecules found abundantly on nerve cells (neurons), especially in the brain. In some individuals, the immune system may wrongly identify these gangliosides as foreign and produce antibodies against them, leading to certain neurological disorders.


  • Profile Name Ganglioside - IgG Antibody Panel by Immunoblot
  • Sample Type Serum
  • Preparations Required No fasting is required. Avoid strenuous exercise and stress before the sample collection. Inform your doctor about all the medications, vitamins, or supplements you are taking.
  • Report Time 6 hours

The immunoblot method, commonly known as Western blot, is a highly sensitive and specific procedure used to detect these antibodies. The test results can help in diagnosing and managing conditions such as Guillain-Barré syndrome (GBS), Miller Fisher syndrome (MFS), and other autoimmune neuropathies.

Home Sample Collection Process

1
Book your convenient slot
Book your convenient slot
2
Sample Collection by Phlebotomist
Sample Collection by Phlebotomist
3
Reporting of the sample at lab
Reporting of the sample at lab
4
Download Reports
Download Reports

Note: Home Sample Collection is only for Pathology lab tests.

Frequently Asked Questions

This is a blood test that identifies the presence of IgG antibodies against gangliosides in the blood, which can be indicative of certain neurological disorders.

This test is ordered when a patient shows signs of a neurological disorder and the doctor suspects an autoimmune cause. The presence of these antibodies can assist in the diagnosis of conditions such as Guillain-Barré syndrome or Miller Fisher syndrome.

The sample is collected via a blood draw from a vein in your arm. This procedure is performed by a trained healthcare professional.

A positive result means that IgG antibodies against gangliosides were detected in your blood. This could indicate the presence of an autoimmune neurological disorder.

If the test results are positive, your doctor will likely order further tests to confirm a diagnosis and determine the best course of treatment.

The test itself carries few risks, other than slight pain or bruising at the needle site.

A negative result means no anti-ganglioside antibodies were detected in your blood. However, if you continue to experience symptoms, your doctor may recommend other tests.

Certain medications may interfere with the results, so it is crucial to inform your doctor of any medications you are currently taking.

If your test results are abnormal, you should consult with a neurologist, as they specialize in disorders of the nervous system.

The frequency of this test depends on your symptoms and the discretion of your doctor.

Symptoms can vary but often include weakness, numbness, tingling, and uncoordinated movements.

Other tests that might be done include a complete blood count, metabolic panel, and other specific antibody tests.

Treatment typically involves managing symptoms and may include medication to suppress or modulate the immune system.

No special preparation is needed for this test.

The test can help confirm a diagnosis but determining the severity or prognosis of a condition usually involves a combination of tests, physical examinations, and symptom assessment.

The Ganglioside - IgG Antibody Panel by Immunoblot is a crucial diagnostic tool in the hands of a neurologist. If you are experiencing symptoms indicative of a neurological disorder, getting this test could be a key step towards receiving the right diagnosis and appropriate treatment. Always remember that understanding your health and treatment options is an essential part of managing any medical condition, so don't hesitate to ask your doctor about any concerns or questions you may have.

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