Autoimmune Hepatitis Panel II provides an in-depth evaluation of autoimmune hepatitis, a disease characterized by the body's immune system launching an attack on liver cells. This results in inflammation and possible liver damage. The panel includes a range of antibodies that can point towards different facets of autoimmune hepatitis, aiding in diagnosis, and treatment planning. Understanding the ins and outs of this test can empower patients and medical professionals in managing liver health effectively.
The Autoimmune Hepatitis Panel II uses an immunofluorescence assay (IFA) to detect the presence of different types of antibodies, including Anti-Mitochondrial Antibody M2 (AMA M2), M2-3E, Sp100, Promyelocytic Leukaemia (PML), gp210, Anti-Liver Kidney Microsome Type 1 (Anti-LKM1), Liver Cytosol Type 1 (LC1), Soluble Liver Antigen/Liver Pancreas (SLA/LP), and Ro52. These antibodies can signify various forms of autoimmune hepatitis and related conditions, making this panel a comprehensive diagnostic tool for autoimmune liver diseases.
Autoimmune hepatitis is categorized into two types based on the antibodies present. Type 1 is associated with anti-nuclear antibodies (ANA), Anti-Smooth Muscle Antibody (ASMA), and at times, SLA/LP. Type 2, though less common, is signified by Anti-LKM1 and LC1 antibodies. Certain antibodies like AMA M2, Sp100, gp210, and PML are primarily linked to primary biliary cholangitis, another autoimmune liver disease. The detection of these antibodies through the Autoimmune Hepatitis Panel II contributes to a more precise diagnosis and helps establish an appropriate treatment plan.
Note: Home Sample Collection is only for Pathology lab tests.
Your doctor may order the Autoimmune Hepatitis Panel II if you are showing signs of liver disease, such as jaundice, fatigue, or discomfort in the abdomen, and autoimmune hepatitis is suspected.
Positive results for different antibodies indicate different types of autoimmune hepatitis or related conditions. For example, positive Anti-LKM1 and LC1 antibodies are suggestive of Type 2 Autoimmune Hepatitis.
No, there is no need to fast before taking the Autoimmune Hepatitis Panel II test. You can continue with your usual diet and fluid intake.
The Autoimmune Hepatitis Panel II uses an immunofluorescence assay (IFA). It's a lab technique that detects specific antibodies in your blood.
Abnormal results suggest the possibility of autoimmune hepatitis or related conditions. However, further investigations will be needed to confirm the diagnosis. If your test results are abnormal, your doctor will suggest appropriate follow-up tests or may refer you to a specialist.
If you have been diagnosed with autoimmune hepatitis, your doctor will determine the frequency of this test based on the progression of your condition and your response to the treatment.
No, the Autoimmune Hepatitis Panel II requires a blood sample to be taken by a healthcare professional. The analysis should be performed in a laboratory.
While the Autoimmune Hepatitis Panel II is primarily designed to help diagnose autoimmune hepatitis, abnormal results can suggest other liver diseases.
If your test values are abnormal, you should consult a hepatologist or gastroenterologist for further evaluation and treatment.
The normal values for the tests in the panel are generally negative. The presence of antibodies suggests the possibility of autoimmune hepatitis or related conditions.
Understanding the nuances of autoimmune hepatitis can make the process of diagnosis and management less overwhelming. This complex condition requires a comprehensive approach for accurate diagnosis, and the Autoimmune Hepatitis Panel II serves as a powerful tool in this endeavor. Timely diagnosis and treatment can prevent severe liver damage, making it crucial to consult your doctor if you suspect any symptoms or abnormalities. Stay proactive and informed to ensure optimal liver health.